Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g3983.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g3983.t1
Gene ID Description PCC Relationship
g3983.t1KELCH PROTEIN1positive
g7212.t1RING FINGER AND CCCH-TYPE ZINC FINGER DOMAIN-CONTAINING PROTEIN0.95positive
g28162.t1DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 410.93positive
g1705.t1SYNDECAN0.93positive
g28086.t1DNAJ HOMOLOG SUBFAMILY B MEMBER 20.93positive
g4897.t1CRUMBS FAMILY MEMBER0.93positive
g10492.t1LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED0.92positive
g6125.t1--0.92positive
g14204.t1MYELIN TRANSCRIPTION FACTOR 1-RELATED0.92positive
g6655.t1FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER0.92positive
g10554.t1OS02G0815200 PROTEIN0.92positive
g35781.t1MYOSIN HEAVY CHAIN, NON-MUSCLE0.91positive
g13997.t1--0.91positive
g1918.t1BCL-2 RELATED0.91positive
g1170.t1TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II0.91positive
g16627.t1EPSIN/ENT-RELATED0.91positive
g5687.t1PUR-TRANSCRIPTIONAL ACTIVATOR0.91positive
g3299.t1REGULATORY-ASSOCIATED PROTEIN OF MTOR0.91positive
g9960.t1EPH RECEPTOR A50.90positive
g5323.t1MULTICOPPER OXIDASE-RELATED0.90positive
g1295.t1DOUBLE ZINC RIBBON AND ANKYRIN REPEAT-CONTAINING PROTEIN 10.90positive
g8996.t1FLOTILLIN-RELATED0.90positive
g8048.t1SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS0.89positive
g28550.t1EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G0.89positive
g13537.t1GLR0591 PROTEIN0.89positive
g7231.t1VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 10.89positive
g32139.t1--0.87positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 145 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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