Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g4067.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g4067.t1
Gene ID Description PCC Relationship
g4067.t1CADHERIN-87A1positive
g5343.t1--0.95positive
g9055.t1UBIQUITIN CARBOXYL-TERMINAL HYDROLASE0.94positive
g787.t1--0.93positive
g19126.t1--0.92positive
g9743.t1GABA-B RECEPTOR0.92positive
g3658.t1SNF2/RAD54 FAMILY MEMBER0.92positive
g5251.t1CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED0.92positive
g19127.t1--0.91positive
g10190.t1EH DOMAIN0.91positive
g7287.t1--0.91positive
g15608.t1MYOSIN0.90positive
g969.t1CENTROSOMAL PROTEIN OF 290 KDA0.90positive
g17942.t1SWI/SNF-RELATED0.90positive
g19377.t1--0.90positive
g4603.t1ADENYLATE CYCLASE TYPE 10.90positive
g32757.t1EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT EIF-30.89positive
g6029.t1DISCS LARGE0.89positive
g16188.t1OVOCHYMASE-RELATED0.87positive
g31769.t1HISTONE H3 METHYLTRANSFERASE0.87positive
g11309.t1--0.87positive
g5299.t1NOVEL ZZ TYPE ZINC FINGER DOMAIN CONTAINING PROTEIN0.86positive
g10366.t1SODIUM/HYDROGEN EXCHANGER0.84positive
g34990.t1MASK PROTEIN0.83positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 87 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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