Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g4160.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g4160.t1
Gene ID Description PCC Relationship
g4160.t1--1positive
g6430.t1SWAP-70 RECOMBINASE0.99positive
g4161.t1MULTICOPPER OXIDASE-RELATED0.98positive
g402.t1--0.98positive
g6505.t1NITRIC OXIDE SYNTHASE-RELATED0.97positive
g12882.t1NNMT/PNMT/TEMT FAMILY MEMBER0.97positive
g6346.t1MERLIN/MOESIN/EZRIN/RADIXIN0.97positive
g5818.t1CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN0.97positive
g11138.t1BANK1/PIK3AP1 FAMILY MEMBER0.97positive
g4804.t1FACTOR VIII-ASSOCIATED GENE 10.97positive
g3404.t1CEREBRAL PROTEIN-11-RELATED0.97positive
g13812.t1RETINOBLASTOMA BINDING PROTEIN 80.97positive
g295.t1--0.97positive
g23610.t1UBIQUITIN THIOESTERASE0.97positive
g2191.t1RUBY-EYE2-LIKE PROTEIN0.97positive
g27122.t1TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN TAB0.96positive
g16112.t1MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE0.96positive
g28027.t1FI24210P10.96positive
g33312.t1KELCH PROTEIN0.96positive
g22100.t13'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN0.96positive
g6432.t1SWAP-70 RECOMBINASE0.96positive
g4159.t1LIG_CHAN-GLU_BD DOMAIN-CONTAINING PROTEIN0.96positive
g22068.t1BONUS, ISOFORM C-RELATED0.96positive
g2568.t1--0.96positive
g10331.t1DEUBIQUITINATING PROTEIN VCIP1350.96positive
g27687.t1DNAJ HOMOLOG SUBFAMILY C MEMBER 170.96positive
g27187.t1UBIQUITIN CARBOXYL-TERMINAL HYDROLASE0.96positive
g20136.t1PHEROMONE SHUTDOWN PROTEIN0.96positive
g314.t1WD REPEAT-CONTAINING PROTEIN 270.96positive
g17718.t1--0.96positive
g2000.t1--0.96positive
g16204.t1GAMETOGENETIN-BINDING PROTEIN 20.96positive
g32018.t1--0.96positive
g633.t1MOLTING PROTEIN MLT-40.96positive
g16764.t1YY1 ASSOCIATED PROTEIN-RELATED0.96positive
g3928.t1BEN DOMAIN-CONTAINING PROTEIN 30.96positive
g5252.t1CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED0.96positive
g19246.t1CYTOCHROME P450 FAMILY 46 SUBFAMILY A0.96positive
g9525.t1-0.95positive
g13539.t1OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL0.95positive
g3586.t1NUCLEAR FRAGILE X MENTAL RETARDATION PROTEIN INTERACTING PROTEIN 10.95positive
g5251.t1CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED0.95positive
g11254.t1SPINSTER0.95positive
g2466.t13-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA GUANINE-N 7 - -METHYLTRANSFERASE0.95positive
g9737.t1--0.95positive
g23744.t1LD33804P0.95positive
g1424.t1--0.95positive
g27303.t1DYSTROGLYCAN-RELATED0.94positive
g16217.t1LD33804P0.94positive
g3313.t1--0.94positive
g25459.t1--0.93positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 374 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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