Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g4161.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g4161.t1
Gene ID Description PCC Relationship
g4161.t1MULTICOPPER OXIDASE-RELATED1positive
g4160.t1--0.98positive
g20136.t1PHEROMONE SHUTDOWN PROTEIN0.97positive
g402.t1--0.97positive
g6430.t1SWAP-70 RECOMBINASE0.97positive
g633.t1MOLTING PROTEIN MLT-40.97positive
g27687.t1DNAJ HOMOLOG SUBFAMILY C MEMBER 170.97positive
g5251.t1CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED0.97positive
g17147.t1--0.96positive
g11138.t1BANK1/PIK3AP1 FAMILY MEMBER0.96positive
g27269.t1ZINC FINGER PROTEIN0.96positive
g16764.t1YY1 ASSOCIATED PROTEIN-RELATED0.96positive
g16919.t1ES-2 PROTEIN - RELATED0.96positive
g5818.t1CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN0.96positive
g6432.t1SWAP-70 RECOMBINASE0.96positive
g22068.t1BONUS, ISOFORM C-RELATED0.96positive
g10331.t1DEUBIQUITINATING PROTEIN VCIP1350.96positive
g28027.t1FI24210P10.96positive
g2000.t1--0.96positive
g6505.t1NITRIC OXIDE SYNTHASE-RELATED0.96positive
g22100.t13'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN0.96positive
g27095.t1RIBONUCLEASE0.95positive
g35378.t1--0.95positive
g12882.t1NNMT/PNMT/TEMT FAMILY MEMBER0.95positive
g2191.t1RUBY-EYE2-LIKE PROTEIN0.95positive
g27303.t1DYSTROGLYCAN-RELATED0.95positive
g314.t1WD REPEAT-CONTAINING PROTEIN 270.95positive
g3318.t1--0.95positive
g23610.t1UBIQUITIN THIOESTERASE0.95positive
g27755.t1HOMER0.95positive
g9525.t1-0.95positive
g2466.t13-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA GUANINE-N 7 - -METHYLTRANSFERASE0.95positive
g17146.t1SORTING NEXIN-29-RELATED0.94positive
g9039.t1ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 60.94positive
g23744.t1LD33804P0.94positive
g12318.t1CLASP0.94positive
g3658.t1SNF2/RAD54 FAMILY MEMBER0.93positive
g11408.t1--0.93positive
g25459.t1--0.93positive
g1976.t1ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER0.92positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 245 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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