Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g4210.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g4210.t1
Gene ID Description PCC Relationship
g4210.t1ASPARTATE AMINOTRANSFERASE1positive
g494.t1OXIDOREDUCTASE HTATIP20.86positive
g3878.t1ADAPTIN, ALPHA/GAMMA/EPSILON0.85positive
g23890.t1KINESIN-RELATED PROTEIN 60.85positive
g14982.t1ANTIGEN MLAA-22-RELATED0.84positive
g28220.t1METALLOPEPTIDASE M28 FAMILY MEMBER0.84positive
g23727.t1ORIGIN RECOGNITION COMPLEX SUBUNIT 40.82positive
g13659.t1TETRASPANIN0.81positive
g14043.t1CYSTEINE DESULFURYLASE FAMILY MEMBER0.76positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). All 10 gene pairs of this network are carried over.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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