Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g4216.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g4216.t1
Gene ID Description PCC Relationship
g4216.t1--1positive
g7175.t1--0.84positive
g16689.t1RETROTRANSPOSON0.84positive
g33541.t1--0.83positive
g13910.t1--0.83positive
g5871.t1--0.82positive
g25211.t1--0.82positive
g31095.t1SI:CH211-108C17.2-RELATED-RELATED0.81positive
g5832.t1RETROTRANSPOSON0.81positive
g28232.t1--0.79positive
g25716.t1HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED0.79positive
g31652.t1--0.79positive
g89.t1INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED0.78positive
g36073.t1RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN0.77positive
g28536.t1PROTEIN CBG266940.77positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 34 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
TOP