Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g4220.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g4220.t1
Gene ID Description PCC Relationship
g4220.t1CYSTEINE-RICH SECRETORY PROTEIN-RELATED1positive
g14627.t1ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA0.99positive
g1938.t1LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED0.99positive
g4013.t1GUANYLYL CYCLASE0.99positive
g12614.t1BONUS, ISOFORM C-RELATED0.99positive
g4893.t1VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS130.99positive
g27014.t1CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A0.99positive
g11666.t1TUMOR PROTEIN P53-INDUCIBLE PROTEIN 110.99positive
g7296.t15-HYDROXYTRYPTAMINE RECEPTOR0.99positive
g14100.t1CENTROSOMAL PROTEIN 20.99positive
g8077.t1VOLTAGE-GATED POTASSIUM CHANNEL0.99positive
g7196.t1SRCR DOMAIN-CONTAINING PROTEIN0.99positive
g11798.t1CUB DOMAIN-CONTAINING PROTEIN0.99positive
g15495.t1CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED0.99positive
g35098.t1TRANSIENT RECEPTOR POTENTIAL CHANNEL0.99positive
g16164.t1TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 130.99positive
g6876.t1CYCLIC NUCLEOTIDE PHOSPHODIESTERASE0.99positive
g31247.t1MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 30.99positive
g4326.t1FIBROBLAST GROWTH FACTOR RECEPTOR0.99positive
g20280.t1TYROSINE-PROTEIN KINASE RECEPTOR0.98positive
g35485.t1MULTICOPPER OXIDASE-RELATED0.98positive
g28360.t1FI19480P10.98positive
g4014.t1GUANYLYL CYCLASE0.98positive
g17699.t1G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE0.98positive
g2539.t1VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM0.98positive
g1102.t1VOLTAGE-GATED POTASSIUM CHANNEL0.98positive
g6231.t1POLYCYSTIN-10.98positive
g27344.t1ECTOPIC P GRANULES PROTEIN 5 HOMOLOG0.98positive
g3168.t1VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL0.98positive
g2006.t1VOLTAGE-GATED POTASSIUM CHANNEL0.98positive
g27767.t1DUAL SPECIFICITY PROTEIN KINASE0.98positive
g22666.t1VOLTAGE-GATED POTASSIUM CHANNEL0.98positive
g5748.t1--0.98positive
g11219.t1ZINC FINGER PROTEIN0.98positive
g28420.t1CYSTEINE-RICH SECRETORY PROTEIN-RELATED0.98positive
g17416.t1--0.98positive
g7197.t1VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED0.98positive
g3023.t1PROPERDIN0.98positive
g12826.t1DNA2/NAM7 HELICASE FAMILY0.98positive
g4277.t1--0.97positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 205 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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