Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g4434.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g4434.t1
Gene ID Description PCC Relationship
g4434.t1FIBRINOGEN/TENASCIN/ANGIOPOEITIN1positive
g27514.t1TRANSLATION ELONGATION FACTOR-RELATED1.00positive
g20856.t1EPH RECEPTOR A51.00positive
g28228.t1TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS1.00positive
g4710.t1THYROTROPIN-RELEASING HORMONE RECEPTOR0.99positive
g27776.t1RIBOSOMAL PROTEIN L5-RELATED0.99positive
g16163.t1TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 130.99positive
g31660.t1SH3 DOMAIN-CONTAINING0.99positive
g15439.t1--0.99positive
g7546.t1--0.99positive
g5679.t1--0.99positive
g528.t1FCH AND DOUBLE SH3 DOMAINS PROTEIN0.99positive
g18961.t1G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER0.99positive
g3925.t1UBIQUITIN-PROTEIN LIGASE E3C0.99positive
g12437.t1SOLUTE CARRIER FAMILY 20.99positive
g27084.t1RADIAL SPOKE HEAD 1 HOMOLOG0.99positive
g22956.t1--0.99positive
g35342.t1BRORIN FAMILY MEMBER0.99positive
g4055.t1--0.99positive
g15941.t1FACIOGENITAL DYSPLASIA PROTEIN0.99positive
g12030.t1COLLAGEN ALPHA0.99positive
g7283.t1AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED0.99positive
g9043.t1METAXIN RELATED0.99positive
g5747.t1ATAXIA TELANGIECTASIA MUTATED ATM -RELATED0.99positive
g27828.t1--0.99positive
g418.t1VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM0.99positive
g19114.t1RECEPTOR FOR ACTIVATED PROTEIN KINASE C RACK10.99positive
g27742.t1--0.99positive
g16168.t1LEUCINE RICH REPEAT FAMILY PROTEIN0.99positive
g6890.t1UNCHARACTERIZED0.99positive
g14564.t1RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 10.99positive
g6446.t1ENDOGLIN/TGF-BETA RECEPTOR TYPE III0.99positive
g12486.t1GLIAL CELLS MISSING RELATED/GLIDE0.99positive
g11343.t1--0.99positive
g13535.t1SODIUM/CALCIUM EXCHANGER0.99positive
g17435.t1VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A0.99positive
g7527.t1--0.99positive
g11889.t1PROSTAGLANDIN G/H SYNTHASE0.99positive
g27468.t1SOLUTE CARRIER FAMILY 22 MEMBER0.99positive
g7800.t1GLUTAMATE SEMIALDEHYDE DEHYDROGENASE0.99positive
g18965.t1CARBOHYDRATE SULFOTRANSFERASE0.99positive
g4327.t1TYROSINE-PROTEIN KINASE RECEPTOR0.99positive
g25713.t1--0.99positive
g16328.t1ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR0.99positive
g7280.t1AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED0.99positive
g19262.t1--0.99positive
g23002.t1CYTOCHROME P450 FAMILY 30.99positive
g12064.t1SAM DOMAIN-CONTAINING PROTEIN-RELATED0.99positive
g9152.t1--0.99positive
g8657.t1CADHERIN-230.98positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 356 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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