Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g4614.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g4614.t1
Gene ID Description PCC Relationship
g4614.t1--1positive
g33805.t1--0.98positive
g15707.t1SOLUTE CARRIER FAMILY 10 MEMBER 70.97positive
g17727.t1ADP RIBOSYLATION FACTOR-RELATED0.97positive
g7727.t1CALRETICULIN AND CALNEXIN0.96positive
g31826.t1DESUMOYLATING ISOPEPTIDASE0.95positive
g3184.t1SORTING NEXIN-22 AND 240.95positive
g12051.t1DISCS LARGE0.95positive
g11859.t1NUCLEAR CAP-BINDING PROTEIN SUBUNIT 30.95positive
g3632.t1METHYLMALONIC ACIDURIA AND HOMOCYSTINURIA TYPE C PROTEIN0.95positive
g1741.t1PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 10.94positive
g6071.t1SYNAPTOTAGMIN 14, ISOFORM D0.94positive
g35803.t1STEERIN0.94positive
g5564.t1B9 DOMAIN-CONTAINING0.94positive
g35076.t1TRACE AMINE-ASSOCIATED RECEPTOR 19N-RELATED0.94positive
g7070.t1DPH3 HOMOLOG-RELATED0.93positive
g32333.t1CARDIOLIPIN HYDROLASE0.93positive
g5240.t1--0.93positive
g15671.t1CHROMATIN TARGET OF PRMT1 PROTEIN0.93positive
g18489.t1--0.93positive
g11787.t1SI:CH211-201H21.5-RELATED0.93positive
g15231.t1ANK_REP_REGION DOMAIN-CONTAINING PROTEIN0.93positive
g8234.t1TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X0.92positive
g8483.t1PHOSPHOLIPASE-RELATED0.92positive
g13907.t1ANTI-SILENCING PROTEIN 10.92positive
g27364.t1ADP RIBOSYLATION FACTOR-RELATED0.92positive
g26926.t1--0.91positive
g8758.t1TUBULIN-SPECIFIC CHAPERONE A0.91positive
g16550.t1COMPLEX III ASSEMBLY FACTOR LYRM70.91positive
g6072.t1SYNAPTOTAGMIN 14, ISOFORM D0.91positive
g6743.t1C5ORF350.90positive
g8812.t1--0.88positive
g18636.t1PEPTIDYL-TRNA HYDROLASE 20.88positive
g19720.t1RING-TYPE DOMAIN-CONTAINING PROTEIN0.85positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 179 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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