Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g4685.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g4685.t1
Gene ID Description PCC Relationship
g4685.t1MUSCLE-SPECIFIC PROTEIN 300 KDA, ISOFORM G1positive
g17.t1ADHESION G-PROTEIN COUPLED RECEPTOR V10.97positive
g32240.t1DYNEIN HEAVY CHAIN FAMILY PROTEIN0.96positive
g4045.t1MALE FERTILITY FACTOR KL50.96positive
g9835.t1DYNEIN HEAVY CHAIN0.96positive
g11107.t1MALE FERTILITY FACTOR KL50.96positive
g2945.t1DYNEIN HEAVY CHAIN FAMILY PROTEIN0.96positive
g10757.t1DYNEIN HEAVY CHAIN0.95positive
g61.t1--0.94positive
g3234.t1DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN0.94positive
g16174.t1SERINE/THREONINE PROTEIN KINASE0.93positive
g27955.t1--0.92positive
g25126.t1CATION TRANSPORTING ATPASE0.91positive
g27244.t1--0.88positive
g17008.t1--0.81positive
g5399.t1MIDASIN-RELATED0.80positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 36 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
TOP