Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g474.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g474.t1
Gene ID Description PCC Relationship
g474.t1SYNAPTOTAGMIN1positive
g444.t1PR DOMAIN ZINC FINGER PROTEIN0.95positive
g31790.t1--0.92positive
g1843.t1AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED0.92positive
g15093.t1NETRIN/LAMININ-RELATED0.92positive
g31956.t1TGF-BETA FAMILY0.91positive
g12975.t1CELL FATE DETERMINING PROTEIN MAB21-RELATED0.91positive
g5414.t1LIPID PHOSPHATE PHOSPHATASE0.91positive
g15579.t1RETROTRANSPOSON0.90positive
g33857.t1THAP DOMAIN-CONTAINING0.90positive
g18503.t1PHD-TYPE DOMAIN-CONTAINING PROTEIN0.90positive
g26116.t1--0.88positive
g615.t1HOMEOBOX PROTEIN NKX0.88positive
g25114.t1TRANSMEMBRANE PROTEIN 121B0.85positive
g25144.t1--0.83positive
g32933.t1D-ALANINE--D-ALANINE LIGASE0.82positive
g31515.t15'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE0.78positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 46 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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