Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g4902.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g4902.t1
Gene ID Description PCC Relationship
g4902.t1--1positive
g28027.t1FI24210P10.95positive
g5326.t1D-GLUCURONYL C5-EPIMERASE0.95positive
g7431.t1--0.95positive
g20136.t1PHEROMONE SHUTDOWN PROTEIN0.95positive
g633.t1MOLTING PROTEIN MLT-40.94positive
g12272.t1SERINE/THREONINE-PROTEIN KINASE 170.94positive
g29348.t1LD33804P0.94positive
g12116.t1REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG0.94positive
g6210.t1METHYLMALONYL-COA MUTASE0.94positive
g23743.t1LD33804P0.94positive
g2532.t1--0.94positive
g11455.t1GLYCOSYLTRANSFERASE0.94positive
g28399.t1--0.93positive
g22794.t1--0.87positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 38 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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