Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g498.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g498.t1
Gene ID Description PCC Relationship
g498.t1AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED1positive
g23600.t1G PROTEIN-COUPLED RECEPTOR0.99positive
g14021.t15-HYDROXYTRYPTAMINE RECEPTOR0.99positive
g3245.t15-HYDROXYTRYPTAMINE RECEPTOR0.99positive
g1886.t1PROPERDIN0.99positive
g7906.t1POLYCYSTIN FAMILY MEMBER0.99positive
g17098.t1OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR0.99positive
g26771.t1TOLL-LIKE RECEPTOR0.99positive
g4517.t1NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR0.99positive
g35342.t1BRORIN FAMILY MEMBER0.99positive
g16902.t1IONOTROPIC GLUTAMATE RECEPTOR0.99positive
g16164.t1TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 130.99positive
g7170.t1MONOCARBOXYLATE TRANSPORTER0.99positive
g12573.t1VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT0.99positive
g528.t1FCH AND DOUBLE SH3 DOMAINS PROTEIN0.99positive
g28228.t1TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS0.99positive
g34877.t1LEUCOKININ RECEPTOR-RELATED0.99positive
g1847.t1VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM0.99positive
g17464.t1BETA-ELIMINATING LYASE-LIKE PROTEIN-RELATED0.98positive
g1797.t1DUAL SERINE/THREONINE AND TYROSINE PROTEIN KINASE0.98positive
g5456.t1--0.98positive
g28661.t1IONOTROPIC GLUTAMATE RECEPTOR0.98positive
g29917.t1TRANSPOSON0.98positive
g11813.t1BETA TRANSDUCIN-RELATED PROTEIN0.97positive
g5606.t1DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER0.96positive
g28250.t1MONOCARBOXYLATE TRANSPORTER0.93positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 92 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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