Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g509.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g509.t1
Gene ID Description PCC Relationship
g509.t1AMINOMETHYLTRANSFERASE1positive
g10156.t1CTP SYNTHASE0.96positive
g16299.t1GC-RICH SEQUENCE DNA-BINDING FACTOR0.96positive
g10197.t1INHIBITOR OF APOPTOSIS0.96positive
g12337.t1--0.96positive
g25009.t1UNCHARACTERIZED0.95positive
g9464.t1CADHERIN-230.95positive
g23806.t1VOLTAGE-GATED POTASSIUM CHANNEL0.95positive
g9871.t1SPLICING FACTOR 45 SPF450.95positive
g7692.t1SERUM RESPONSE FACTOR-BINDING0.95positive
g28073.t1GLYCINE N-METHYLTRANSFERASE0.94positive
g16719.t1N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE0.94positive
g15613.t1T-BOX PROTEIN-RELATED0.94positive
g16927.t1SYNEMBRYN0.94positive
g6476.t1PHD/F-BOX CONTAINING PROTEIN0.94positive
g6655.t1FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER0.94positive
g3679.t1TRANSLATION INITIATION FACTOR IF-30.94positive
g34144.t1BLOC-1-RELATED COMPLEX SUBUNIT 50.94positive
g5142.t1UBIQUITIN-CONJUGATING ENZYME E20.94positive
g13537.t1GLR0591 PROTEIN0.93positive
g28015.t1RHO FAMILY GTPASE0.93positive
g1295.t1DOUBLE ZINC RIBBON AND ANKYRIN REPEAT-CONTAINING PROTEIN 10.93positive
g33211.t1--0.93positive
g23336.t1--0.93positive
g30135.t1TESTIS DEVELOPMENT PROTEIN PRTD0.87positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 85 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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