Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g5326.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g5326.t1
Gene ID Description PCC Relationship
g5326.t1D-GLUCURONYL C5-EPIMERASE1positive
g12341.t1TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870)0.97positive
g28027.t1FI24210P10.96positive
g2532.t1--0.96positive
g3404.t1CEREBRAL PROTEIN-11-RELATED0.96positive
g7431.t1--0.96positive
g29384.t1--0.96positive
g15081.t1-0.96positive
g9525.t1-0.96positive
g23138.t1UBIQUITIN SPECIFIC PROTEINASE0.96positive
g23743.t1LD33804P0.96positive
g633.t1MOLTING PROTEIN MLT-40.95positive
g4500.t1RIKEN CDNA 9930021J03 GENE0.95positive
g3586.t1NUCLEAR FRAGILE X MENTAL RETARDATION PROTEIN INTERACTING PROTEIN 10.95positive
g6210.t1METHYLMALONYL-COA MUTASE0.95positive
g920.t1FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I0.95positive
g22100.t13'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN0.95positive
g572.t1ACTIN0.95positive
g4902.t1--0.95positive
g20136.t1PHEROMONE SHUTDOWN PROTEIN0.95positive
g27754.t1HOMER0.95positive
g27362.t1ANDROGEN-INDUCED PROTEIN 1-RELATED0.95positive
g11254.t1SPINSTER0.95positive
g28813.t1TRANS-ACONITATE 2-METHYLTRANSFERASE-RELATED0.95positive
g9628.t1HERMANSKY-PUDLAK SYNDROME 6 PROTEIN0.95positive
g2000.t1--0.95positive
g10641.t1DYNEIN LIGHT INTERMEDIATE CHAIN0.95positive
g2179.t1NUCLEOPHOSMIN0.95positive
g19336.t1CELL FATE DETERMINING PROTEIN MAB21-RELATED0.94positive
g8358.t1GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED0.94positive
g1424.t1--0.94positive
g28445.t1CYTOCHROME P450 FAMILY 46 SUBFAMILY A0.94positive
g11455.t1GLYCOSYLTRANSFERASE0.94positive
g21236.t1PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER0.94positive
g7810.t1CHIMERIN FAMILY MEMBER0.94positive
g1834.t1TETRATRICOPEPTIDE REPEAT (TPR)-LIKE SUPERFAMILY PROTEIN-RELATED0.94positive
g22087.t1OVOCHYMASE-RELATED0.94positive
g27302.t1GLYCERATE KINASE0.93positive
g6006.t1PHOSPHOLIPASE D - RELATED0.92positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 239 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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