Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g5349.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g5349.t1
Gene ID Description PCC Relationship
g5349.t1FAMILY WITH SEQUENCE SIMILARITY 216 MEMBER A1positive
g30127.t1--0.98positive
g32099.t1METABOTROPIC GLUTAMATE RECEPTOR0.98positive
g6644.t1REGULATOR OF G PROTEIN SIGNALING0.97positive
g4748.t1--0.97positive
g8455.t1MULTI-COPPER OXIDASE0.97positive
g17292.t1ENDOGLIN/TGF-BETA RECEPTOR TYPE III0.97positive
g22212.t1PHD-TYPE DOMAIN-CONTAINING PROTEIN0.97positive
g34363.t1STEP II SPLICING FACTOR SLU70.96positive
g27458.t1NEUROPEPTIDE Y RECEPTOR0.96positive
g20833.t1F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED0.96positive
g23590.t1TYROSINE-PROTEIN KINASE RECEPTOR0.96positive
g19831.t1PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 40.96positive
g2719.t1GLR0591 PROTEIN0.96positive
g5792.t1SI:CH211-108C17.2-RELATED-RELATED0.96positive
g8495.t1SERINE/THREONINE-PROTEIN KINASE0.96positive
g35967.t1--0.96positive
g10532.t1RETROTRANSPOSON0.96positive
g23558.t1--0.95positive
g26846.t1--0.95positive
g6502.t1CCCH ZINC FINGER/TIS11-RELATED0.95positive
g12319.t1GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED0.95positive
g8973.t1ANKYRIN REPEAT-CONTAINING0.95positive
g34869.t1DNA-DIRECTED RNA POLYMERASE0.95positive
g24687.t1--0.94positive
g18749.t1--0.94positive
g34607.t1--0.94positive
g17647.t1RETROTRANSPOSON0.94positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 104 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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