Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g5564.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g5564.t1
Gene ID Description PCC Relationship
g5564.t1B9 DOMAIN-CONTAINING1positive
g3184.t1SORTING NEXIN-22 AND 240.96positive
g19206.t1UNCHARACTERIZED0.96positive
g13907.t1ANTI-SILENCING PROTEIN 10.96positive
g20493.t1LD44762P0.96positive
g3035.t1ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD0.95positive
g379.t1AP-5 COMPLEX SUBUNIT MU-10.95positive
g17896.t1PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 10.95positive
g1741.t1PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 10.95positive
g2524.t1MYOSIN LIGHT CHAIN 1, 30.95positive
g6485.t1KIN17 KIN, ANTIGENIC DETERMINANT OF RECA PROTEIN HOMOLOG0.95positive
g14959.t1RAN GTPASE-ACTIVATING PROTEIN 10.94positive
g640.t1UNCHARACTERIZED0.94positive
g2939.t1DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE0.94positive
g18489.t1--0.94positive
g3932.t1--0.94positive
g12005.t1TELOMERE LENGTH AND SILENCING PROTEIN 1 TLS1 FAMILY MEMBER0.94positive
g3984.t1DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED0.94positive
g27739.t1POTASSIUM CHANNEL, SUBFAMILY K0.94positive
g31428.t1NEUROTRANSMITTER GATED ION CHANNEL0.94positive
g13770.t1PROTEIN PHOSPHATASE 2C0.94positive
g15231.t1ANK_REP_REGION DOMAIN-CONTAINING PROTEIN0.94positive
g5240.t1--0.94positive
g3590.t1ATP-BINDING CASSETTE SUB-FAMILY C0.94positive
g4614.t1--0.94positive
g3275.t1--0.93positive
g28859.t1SORBITOL DEHYDROGENASE0.93positive
g2574.t1INOSITOL POLYPHOSPHATE KINASE0.93positive
g2578.t1SPERM PROTEIN HOMOLOG0.93positive
g15807.t1--0.92positive
g25341.t1PROTEIN SIDEKICK0.92positive
g16899.t1--0.92positive
g11787.t1SI:CH211-201H21.5-RELATED0.91positive
g20581.t1--0.91positive
g15719.t1PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNZ1-RELATED0.88positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 213 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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