Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g5635.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g5635.t1
Gene ID Description PCC Relationship
g5635.t1RMLC-LIKE JELLY ROLL FOLD PROTEIN1positive
g480.t1RNA-BINDING PROTEIN 8A0.95positive
g13321.t1TETRATRICOPEPTIDE REPEAT PROTEIN 50.94positive
g11137.t1MUSCLEBLIND-LIKE PROTEIN0.94positive
g14178.t1APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS0.93positive
g12825.t1HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER0.93positive
g2031.t1--0.92positive
g23509.t1SAP180.92positive
g913.t1DNA-DIRECTED RNA POLYMERASE SUBUNIT K0.92positive
g20241.t1HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER0.91positive
g6217.t1HISTONE H2A0.91positive
g20896.t1PHOSPHOGLYCOLATE PHOSPHATASE0.90positive
g9173.t1SER/THR PROTEIN KINASE-TRB0.90positive
g18835.t1RHO GDP-DISSOCIATION INHIBITOR0.90positive
g16659.t1U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A0.90positive
g19288.t1DRAB11-RELATED0.90positive
g9877.t1POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 30.89positive
g1275.t1ADDUCIN0.88positive
g5011.t1TANDEM PH DOMAIN CONTAINING PROTEIN0.87positive
g18043.t1ZGC:1951700.85positive
g25010.t1--0.83positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 107 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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