Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g5643.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g5643.t1
Gene ID Description PCC Relationship
g5643.t1PR DOMAIN ZINC FINGER PROTEIN1positive
g13688.t1UNCHARACTERIZED0.96positive
g16274.t1POLY [ADP-RIBOSE] POLYMERASE0.96positive
g6625.t1TRANSCRIPTION FACTOR-LIKE 5 PROTEIN0.96positive
g35594.t1DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT0.94positive
g16784.t1TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED0.92positive
g28265.t1SER/THR-PROTEIN KINASE RIO20.92positive
g10734.t1DNAJ HOMOLOG SUBFAMILY C MEMBER 160.92positive
g1541.t1UNCHARACTERIZED0.92positive
g21382.t1DNA2/NAM7 HELICASE FAMILY0.92positive
g596.t1N-ACETYLGALACTOSAMINYLTRANSFERASE0.92positive
g35042.t1WD REPEAT DOMAIN-CONTAINING FAMILY0.91positive
g35418.t1ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 10.91positive
g16896.t1SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER0.91positive
g11026.t1RNA RECOGNITION MOTIF-CONTAINING0.90positive
g5217.t1FORMIN HOMOLOGY 2 FAMILY MEMBER0.90positive
g34910.t1MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B0.90positive
g8874.t1CYTOSOLIC PHOSPHOLIPASE A20.90positive
g15353.t1UBIQUITIN-CONJUGATING ENZYME E20.90positive
g5617.t1CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS0.90positive
g29060.t1MOLTING PROTEIN MLT-40.90positive
g19714.t1LD33804P0.89positive
g305.t1--0.89positive
g27171.t1RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING0.89positive
g5095.t1MITOGEN-ACTIVATED PROTEIN KINASE0.89positive
g308.t1CENTROSOMAL PROTEIN KIZUNA0.89positive
g33085.t1MULTICOPPER OXIDASE-RELATED0.88positive
g2374.t1PROTEIN FAM220A0.88positive
g23617.t1--0.88positive
g13640.t1SPHINGOSINE KINASE0.88positive
g3207.t1--0.88positive
g2797.t1BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR0.88positive
g13534.t1AHD DOMAIN-CONTAINING PROTEIN0.87positive
g8340.t1SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 40.87positive
g3297.t1PERFORIN-LIKE PROTEIN 10.84positive
g11157.t1--0.81positive
g24219.t1--0.80positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 198 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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