Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g5669.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g5669.t1
Gene ID Description PCC Relationship
g5669.t1ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL1positive
g6808.t1METALLOPHOSPHOESTERASE0.97positive
g32586.t1--0.96positive
g8000.t1E3 UBIQUITIN-PROTEIN LIGASE HECTD30.96positive
g4813.t1HEADCASE PROTEIN0.96positive
g16763.t1--0.96positive
g35990.t1ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 140.96positive
g8898.t1RASSF0.96positive
g5819.t1CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN0.96positive
g16754.t1HEME OXYGENASE0.96positive
g7920.t1ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED0.95positive
g14208.t1LOQUACIOUS, ISOFORM B0.95positive
g13421.t1TUBULIN POLYGLUTAMYLASE COMPLEX SUBUNIT 10.95positive
g15797.t1UNCHARACTERIZED RING FINGER-CONTAINING PROTEIN0.95positive
g29810.t1--0.95positive
g11802.t1--0.95positive
g10331.t1DEUBIQUITINATING PROTEIN VCIP1350.95positive
g29064.t1RAB FAMILY0.94positive
g12932.t1--0.93positive
g13540.t1--0.89positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 58 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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