Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g5758.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g5758.t1
Gene ID Description PCC Relationship
g5758.t1MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM221positive
g20119.t1TRANSLOCON-ASSOCIATED PROTEIN, BETA SUBUNIT PRECURSOR TRAP-BETA SIGNAL SEQUENCE RECEPTOR BETA SUBUNIT0.98positive
g17242.t1PROTEASOME SUBUNIT ALPHA/BETA0.97positive
g19430.t1UNCHARACTERIZED0.97positive
g11582.t1BRIX DOMAIN CONTAINING PROTEIN0.97positive
g14214.t1PROTEASOME SUBUNIT ALPHA/BETA0.97positive
g27410.t1METALLOPROTEASE TLDD0.97positive
g3876.t1TRANS-SULFURATION ENZYME FAMILY MEMBER0.97positive
g11405.t1MICROSOMAL SIGNAL PEPTIDASE 25 KDA SUBUNIT0.97positive
g30074.t1--0.97positive
g2889.t1PROTEASOME SUBUNIT ALPHA/BETA0.97positive
g28714.t1METALLOPROTEASE TLDD0.97positive
g16319.t1SOMETHING ABOUT SILENCING PROTEIN 10-RELATED0.97positive
g12697.t1COATOMER SUBUNIT EPSILON0.96positive
g2887.t1PROTEASOME SUBUNIT ALPHA/BETA0.96positive
g23524.t1ATP SYNTHASE DELTA/EPSILON CHAIN0.96positive
g33940.t1--0.96positive
g33909.t1--0.96positive
g27049.t1CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT10.96positive
g4524.t1WD REPEAT-CONTAINING PROTEIN 550.96positive
g1530.t1--0.96positive
g26163.t1SERINE-THREONINE PROTEIN KINASE0.96positive
g4728.t1DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE0.96positive
g21886.t1DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT0.96positive
g1567.t126S PROTEASOME NON-ATPASE REGULATORY SUBUNIT0.96positive
g12330.t1SUGAR KINASE0.96positive
g17649.t1NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 8, MITOCHONDRIAL0.95positive
g21836.t1P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASES SUPERFAMILY PROTEIN0.95positive
g21069.t1EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN0.95positive
g19466.t1UNCHARACTERIZED0.95positive
g1303.t1EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 110.95positive
g3012.t1FLAVIN MONOAMINE OXIDASE0.95positive
g14327.t1MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S100.95positive
g5997.t1--0.95positive
g2575.t1--0.95positive
g2816.t126S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 90.95positive
g7902.t1PROTEASOME SUBUNIT ALPHA/BETA0.94positive
g15227.t1AGAP005574-PA0.94positive
g2338.t1CYTOCHROME C OXIDASE POLYPEPTIDE VIA0.94positive
g7383.t1ARP2/3 COMPLEX 20 KD SUBUNIT0.94positive
g33809.t1--0.93positive
g33884.t1GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-20.92positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 263 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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