Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g5760.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g5760.t1
Gene ID Description PCC Relationship
g5760.t1--1positive
g20307.t1INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1-BINDING PROTEIN 10.95positive
g10540.t1SMALL INTEGRAL MEMBRANE PROTEIN 120.95positive
g15967.t1CULLIN0.95positive
g837.t1--0.95positive
g7938.t1RP42 RELATED0.94positive
g17021.t1CYSTEINE-RICH PDZ-BINDING PROTEIN0.94positive
g25206.t1CYCLIN0.93positive
g7058.t1PROTEIN FAM181B0.93positive
g640.t1UNCHARACTERIZED0.93positive
g2939.t1DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE0.93positive
g5530.t1RHOPHILIN0.93positive
g10498.t1DIACYLGLYCEROL O-ACYLTRANSFERASE0.93positive
g27739.t1POTASSIUM CHANNEL, SUBFAMILY K0.93positive
g27602.t1ACROSIN-RELATED0.92positive
g9971.t1CHARGED MULTIVESICULAR BODY PROTEIN0.92positive
g15840.t1TNF RECEPTOR ASSOCIATED FACTOR0.92positive
g2026.t1DNAJ HOMOLOG SUBFAMILY B MEMBER 20.91positive
g27018.t1RNA-BINDING MOTIF PROTEIN, X-LINKED 20.90positive
g15719.t1PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNZ1-RELATED0.90positive
g36482.t1--0.88positive
g27903.t1THAP DOMAIN PROTEIN0.81positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 81 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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