Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g596.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g596.t1
Gene ID Description PCC Relationship
g596.t1N-ACETYLGALACTOSAMINYLTRANSFERASE1positive
g15353.t1UBIQUITIN-CONJUGATING ENZYME E20.95positive
g35418.t1ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 10.94positive
g18295.t1--0.94positive
g27358.t1FORMIMINOTRANSFERASE-CYCLODEAMINASE0.94positive
g2374.t1PROTEIN FAM220A0.92positive
g1541.t1UNCHARACTERIZED0.92positive
g14851.t1TATA-BOX BINDING PROTEIN0.92positive
g16784.t1TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED0.92positive
g5643.t1PR DOMAIN ZINC FINGER PROTEIN0.92positive
g2597.t1PR DOMAIN ZINC FINGER PROTEIN0.92positive
g832.t1TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED-RELATED0.91positive
g21540.t1BTB/POZ DOMAIN-CONTAINING0.91positive
g11990.t1PHOSPHATIDYLCHOLINE TRANSFER PROTEIN0.91positive
g28265.t1SER/THR-PROTEIN KINASE RIO20.91positive
g13688.t1UNCHARACTERIZED0.91positive
g4221.t1OVOCHYMASE-RELATED0.91positive
g16274.t1POLY [ADP-RIBOSE] POLYMERASE0.90positive
g1436.t1PHOSPHATIDYLSERINE DECARBOXYLASE0.90positive
g29767.t1CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 10.90positive
g5617.t1CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS0.90positive
g19930.t1--0.90positive
g17413.t1ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN0.89positive
g14000.t1LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN0.89positive
g22244.t1RETINOL DEHYDROGENASE0.88positive
g34910.t1MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B0.88positive
g21263.t1PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED0.88positive
g13640.t1SPHINGOSINE KINASE0.88positive
g14181.t1SOLUTE CARRIER FAMILY 350.88positive
g26937.t1CULTURE SPECIFIC PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00130)-RELATED0.87positive
g14421.t1G-PROTEIN COUPLED RECEPTOR0.87positive
g13534.t1AHD DOMAIN-CONTAINING PROTEIN0.87positive
g14397.t1VESICLE-ASSOCIATED MEMBRANE PROTEIN 40.86positive
g34908.t1--0.85positive
g24219.t1--0.85positive
g11157.t1--0.84positive
g22877.t1BTB/POZ DOMAIN-CONTAINING0.83positive
g25205.t1--0.83positive
g17244.t1OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR0.81positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 191 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
TOP