Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g5997.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g5997.t1
Gene ID Description PCC Relationship
g5997.t1--1positive
g33940.t1--0.99positive
g30074.t1--0.98positive
g33909.t1--0.97positive
g23524.t1ATP SYNTHASE DELTA/EPSILON CHAIN0.96positive
g3012.t1FLAVIN MONOAMINE OXIDASE0.95positive
g6269.t1--0.95positive
g7181.t1EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G0.95positive
g20195.t1--0.95positive
g5758.t1MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM220.95positive
g12697.t1COATOMER SUBUNIT EPSILON0.95positive
g32162.t1METHANETHIOL OXIDASE0.95positive
g10828.t1MONOCARBOXYLATE TRANSPORTER0.95positive
g17649.t1NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 8, MITOCHONDRIAL0.95positive
g31190.t1DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING0.95positive
g74.t1COILED-COIL DOMAIN-CONTAINING PROTEIN 1580.95positive
g32252.t1METHYLTRANSFERASE0.94positive
g19918.t1HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED0.94positive
g19466.t1UNCHARACTERIZED0.94positive
g21836.t1P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASES SUPERFAMILY PROTEIN0.94positive
g2621.t1--0.93positive
g6677.t1SI:CH211-108C17.2-RELATED-RELATED0.93positive
g26090.t1F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED0.93positive
g24006.t1COLLAGEN ALPHA0.92positive
g34948.t1ATP-BINDING CASSETTE SUB-FAMILY B0.91positive
g6159.t1INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED0.88positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 126 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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