Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g6125.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g6125.t1
Gene ID Description PCC Relationship
g6125.t1--1positive
g8048.t1SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS0.95positive
g3299.t1REGULATORY-ASSOCIATED PROTEIN OF MTOR0.95positive
g5687.t1PUR-TRANSCRIPTIONAL ACTIVATOR0.95positive
g6655.t1FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER0.95positive
g5324.t1PX DOMAIN-CONTAINING PROTEIN0.94positive
g7212.t1RING FINGER AND CCCH-TYPE ZINC FINGER DOMAIN-CONTAINING PROTEIN0.94positive
g14407.t1LD33695P0.94positive
g35781.t1MYOSIN HEAVY CHAIN, NON-MUSCLE0.94positive
g5323.t1MULTICOPPER OXIDASE-RELATED0.94positive
g23976.t1SODIUM/CALCIUM EXCHANGER0.94positive
g5601.t1LONG-CHAIN-FATTY-ACID--COA LIGASE0.94positive
g1170.t1TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II0.94positive
g1295.t1DOUBLE ZINC RIBBON AND ANKYRIN REPEAT-CONTAINING PROTEIN 10.94positive
g5560.t1STRIATIN0.94positive
g2982.t1USP DOMAIN-CONTAINING PROTEIN0.93positive
g6654.t1FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER0.93positive
g16775.t1SHC TRANSFORMING PROTEIN0.93positive
g8880.t1--0.92positive
g4425.t1ALPHA-MANNOSIDE BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE0.92positive
g3301.t1REGULATORY-ASSOCIATED PROTEIN OF MTOR0.92positive
g10492.t1LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED0.92positive
g1296.t1MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK0.92positive
g13997.t1--0.92positive
g3983.t1KELCH PROTEIN0.92positive
g9960.t1EPH RECEPTOR A50.92positive
g28162.t1DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 410.91positive
g9056.t1CUE DOMAIN CONTAINING PROTEIN 10.91positive
g28086.t1DNAJ HOMOLOG SUBFAMILY B MEMBER 20.91positive
g27283.t1PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 70.91positive
g10600.t1F-BOX ONLY PROTEIN0.91positive
g25122.t14.1 G PROTEIN0.91positive
g27639.t1--0.91positive
g7772.t1--0.90positive
g32426.t1--0.90positive
g1781.t1HMG-BOX TRANSCRIPTION FACTOR BBX0.90positive
g3882.t1SERINE/THREONINE-PROTEIN KINASE0.89positive
g12800.t1--0.88positive
g33812.t1--0.88positive
g25512.t1SGNH_HYDRO DOMAIN-CONTAINING PROTEIN0.88positive
g24881.t1--0.87positive
g30135.t1TESTIS DEVELOPMENT PROTEIN PRTD0.87positive
g25659.t1SGNH_HYDRO DOMAIN-CONTAINING PROTEIN0.85positive
g6868.t1LEISHMANOLYSIN-LIKE PEPTIDASE0.82positive
g1168.t1EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN0.73positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 243 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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