Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g6189.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g6189.t1
Gene ID Description PCC Relationship
g6189.t1LEUCOKININ RECEPTOR-RELATED1positive
g28123.t1POTASSIUM CHANNEL, SUBFAMILY K0.99positive
g28044.t1HOMEO BOX HB9 LIKE A-RELATED0.99positive
g7911.t1SYNAPSIN0.99positive
g12486.t1GLIAL CELLS MISSING RELATED/GLIDE0.99positive
g27130.t1BITESIZE, ISOFORM I0.99positive
g63.t1--0.99positive
g30907.t1INTELECTIN0.99positive
g25261.t1HYALURONIC ACID-BINDING PROTEIN 40.99positive
g15219.t1LIM/HOMEOBOX PROTEIN LHX0.99positive
g27403.t1HYALURONIC ACID-BINDING PROTEIN 40.99positive
g2866.t1--0.99positive
g13375.t1--0.98positive
g27475.t1--0.98positive
g5435.t1CARBOHYDRATE SULFOTRANSFERASE0.98positive
g6844.t1PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED0.98positive
g16748.t1--0.98positive
g30726.t1--0.98positive
g23657.t1INTELECTIN0.98positive
g23344.t1INTELECTIN0.98positive
g3362.t1TUBULIN0.98positive
g1665.t1TOLL-LIKE RECEPTOR0.98positive
g3743.t1S -2-HYDROXY-ACID OXIDASE-RELATED0.98positive
g15767.t1DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING0.98positive
g15630.t1--0.95positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 98 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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