Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g6267.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g6267.t1
Gene ID Description PCC Relationship
g6267.t1MYOSIN LIGHT CHAIN 1, 31positive
g7511.t1TUBULIN MONOGLYCYLASE TTLL30.90positive
g33510.t1DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN0.89positive
g26228.t1TRANSKETOLASE0.89positive
g18.t1ADHESION G-PROTEIN COUPLED RECEPTOR V10.89positive
g28887.t1GLUTAMATE CYSTEINE LIGASE REGULATORY SUBUNIT0.88positive
g14709.t1ADIPOLIN0.88positive
g4998.t1NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED0.87positive
g2383.t1NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED0.87positive
g2080.t1ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE0.87positive
g35623.t1--0.87positive
g27416.t1RAS GTPASE-ACTIVATING PROTEINS0.86positive
g9961.t1ATAXIA TELANGIECTASIA MUTATED ATM -RELATED0.86positive
g6601.t1EPITHELIAL CELL-TRANSFORMING SEQUENCE 2 ONCOGENE-LIKE0.85positive
g9141.t1GLYCOGEN PHOSPHORYLASE0.85positive
g21851.t1DELETED IN LUNG AND ESOPHAGEAL CANCER PROTEIN 10.85positive
g446.t1PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE0.85positive
g5478.t1SERINE PROTEASE INHIBITOR0.84positive
g5144.t1SUBGROUP IIII AMINOTRANSFERASE0.84positive
g28077.t1PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE0.84positive
g23238.t1EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED0.84positive
g13204.t1ACETYL-COA CARBOXYLASE, ISOFORM A0.83positive
g10547.t1NACHT, LRR AND CARD DOMAINS-CONTAINING0.83positive
g1474.t1DEP DOMAIN PROTEIN0.83positive
g11986.t1PHOSPHORYLASE B KINASE REGULATORY SUBUNIT0.82positive
g6753.t1--0.80positive
g27082.t1-0.80positive
g1969.t1CELL FATE DETERMINING PROTEIN MAB21-RELATED0.79positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 117 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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