Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g6430.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g6430.t1
Gene ID Description PCC Relationship
g6430.t1SWAP-70 RECOMBINASE1positive
g5818.t1CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN0.99positive
g4160.t1--0.99positive
g4804.t1FACTOR VIII-ASSOCIATED GENE 10.98positive
g13812.t1RETINOBLASTOMA BINDING PROTEIN 80.98positive
g11138.t1BANK1/PIK3AP1 FAMILY MEMBER0.98positive
g17147.t1--0.98positive
g3404.t1CEREBRAL PROTEIN-11-RELATED0.98positive
g33312.t1KELCH PROTEIN0.98positive
g6207.t1--0.98positive
g5819.t1CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN0.98positive
g1839.t1ANOCTAMIN0.97positive
g12882.t1NNMT/PNMT/TEMT FAMILY MEMBER0.97positive
g27357.t1-0.97positive
g10331.t1DEUBIQUITINATING PROTEIN VCIP1350.97positive
g8992.t1--0.97positive
g9738.t1GTP-BINDING PROTEIN ALPHA SUBUNIT0.97positive
g6505.t1NITRIC OXIDE SYNTHASE-RELATED0.97positive
g11633.t1TRANSCRIPTIONAL ADAPTER 10.97positive
g15363.t1RIBONUCLEASE0.97positive
g4161.t1MULTICOPPER OXIDASE-RELATED0.97positive
g402.t1--0.97positive
g35990.t1ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 140.97positive
g22100.t13'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN0.97positive
g16764.t1YY1 ASSOCIATED PROTEIN-RELATED0.97positive
g18371.t1DELTEX-RELATED0.97positive
g2191.t1RUBY-EYE2-LIKE PROTEIN0.97positive
g27187.t1UBIQUITIN CARBOXYL-TERMINAL HYDROLASE0.97positive
g23610.t1UBIQUITIN THIOESTERASE0.97positive
g8719.t1QUIESCIN Q6-RELATED SULFHYDRYL OXIDASE0.97positive
g16763.t1--0.97positive
g19246.t1CYTOCHROME P450 FAMILY 46 SUBFAMILY A0.97positive
g3095.t1E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED0.97positive
g18870.t1SYNDROMES PUTATIVE CHAPERONIN-RELATED0.96positive
g14510.t1MITOGEN-ACTIVATED PROTEIN KINASE0.96positive
g4500.t1RIKEN CDNA 9930021J03 GENE0.96positive
g29384.t1--0.96positive
g27687.t1DNAJ HOMOLOG SUBFAMILY C MEMBER 170.96positive
g16204.t1GAMETOGENETIN-BINDING PROTEIN 20.96positive
g27269.t1ZINC FINGER PROTEIN0.96positive
g28295.t1NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR0.96positive
g633.t1MOLTING PROTEIN MLT-40.96positive
g20509.t1RING FINGER AND SRY DOMAIN-CONTAINING0.96positive
g16112.t1MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE0.96positive
g3318.t1--0.96positive
g6432.t1SWAP-70 RECOMBINASE0.96positive
g32018.t1--0.96positive
g11802.t1--0.96positive
g11254.t1SPINSTER0.95positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 397 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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