Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g6432.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g6432.t1
Gene ID Description PCC Relationship
g6432.t1SWAP-70 RECOMBINASE1positive
g4160.t1--0.96positive
g4161.t1MULTICOPPER OXIDASE-RELATED0.96positive
g6430.t1SWAP-70 RECOMBINASE0.96positive
g13812.t1RETINOBLASTOMA BINDING PROTEIN 80.96positive
g1424.t1--0.96positive
g10331.t1DEUBIQUITINATING PROTEIN VCIP1350.95positive
g17147.t1--0.95positive
g402.t1--0.95positive
g27269.t1ZINC FINGER PROTEIN0.95positive
g3404.t1CEREBRAL PROTEIN-11-RELATED0.95positive
g12882.t1NNMT/PNMT/TEMT FAMILY MEMBER0.95positive
g27687.t1DNAJ HOMOLOG SUBFAMILY C MEMBER 170.95positive
g35539.t1EXPORTIN-60.95positive
g16764.t1YY1 ASSOCIATED PROTEIN-RELATED0.95positive
g2000.t1--0.95positive
g22100.t13'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN0.95positive
g3928.t1BEN DOMAIN-CONTAINING PROTEIN 30.94positive
g5251.t1CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED0.94positive
g27095.t1RIBONUCLEASE0.94positive
g27303.t1DYSTROGLYCAN-RELATED0.94positive
g34024.t1LD33804P0.92positive
g5496.t1HL01030P-RELATED0.92positive
g25505.t1LD33804P0.91positive
g27355.t1--0.89positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 107 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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