Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g6489.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g6489.t1
Gene ID Description PCC Relationship
g6489.t1HOMEOBOX PROTEIN TRANSCRIPTION FACTORS1positive
g9058.t1--0.95positive
g489.t1PWWP DOMAIN-CONTAINING DNA REPAIR FACTOR 3 FAMILY MEMBER0.95positive
g15238.t1GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN0.95positive
g17518.t1DRAB5-RELATED0.94positive
g22689.t1METAL TRANSPORTER CNNM0.94positive
g8164.t1--0.94positive
g15943.t1CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS0.94positive
g1294.t1--0.94positive
g6314.t1--0.94positive
g3326.t1CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS0.93positive
g24733.t1CXC DOMAIN-CONTAINING PROTEIN-RELATED0.93positive
g10324.t1SPLICING FACTOR 3B, SUBUNIT 1-RELATED0.93positive
g25804.t1TRANSPOSON0.93positive
g9174.t1SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 10.92positive
g1830.t1PROTEIN DIAPHANOUS0.92positive
g2433.t1-0.91positive
g19445.t1PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 120.90positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 44 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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