Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g6584.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g6584.t1
Gene ID Description PCC Relationship
g6584.t1GATA-TYPE ZINC FINGER PROTEIN 11positive
g27270.t1BOULE-RELATED0.98positive
g20604.t1SPOT14 FAMILY MEMBER0.97positive
g6271.t1CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN0.97positive
g2867.t1GLYCOPROTEIN HORMONE RECEPTOR0.97positive
g16665.t1ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN0.97positive
g5767.t1UNCHARACTERIZED0.97positive
g21084.t1TRANSLATION FACTOR GUF1-RELATED0.96positive
g27357.t1-0.96positive
g4804.t1FACTOR VIII-ASSOCIATED GENE 10.96positive
g1243.t1TOLL-LIKE RECEPTOR0.96positive
g22068.t1BONUS, ISOFORM C-RELATED0.96positive
g1679.t1BETA-HEXOSAMINIDASE0.96positive
g1478.t1--0.96positive
g11711.t1BATTENIN0.96positive
g18671.t1BATTENIN0.96positive
g2568.t1--0.96positive
g659.t1--0.96positive
g2998.t1ENHANCER OF POLYCOMB0.96positive
g15757.t1UNCHARACTERIZED0.95positive
g23270.t1EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I0.95positive
g22788.t1SPERMATOGENESIS-ASSOCIATED PROTEIN 2/TAMOZHENNIC0.95positive
g9788.t1--0.95positive
g10783.t1--0.94positive
g32331.t1ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN0.94positive
g9341.t1RIBOSOMAL PROTEIN L130.93positive
g34295.t1POTE ANKYRIN DOMAIN0.88positive
g7577.t1ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN-RELATED0.84positive
g27829.t1TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS0.81positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 162 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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