Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g6614.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g6614.t1
Gene ID Description PCC Relationship
g6614.t1COLLAGEN ALPHA1positive
g17806.t1COLLAGEN ALPHA1.00positive
g34677.t1COLLAGEN ALPHA1.00positive
g27385.t1MICROSOMAL DIPEPTIDASE0.99positive
g34663.t1SI:CH211-266K2.10.99positive
g17621.t1--0.99positive
g12961.t1T-BOX PROTEIN-RELATED0.99positive
g13454.t1NEUROTRANSMITTER GATED ION CHANNEL0.99positive
g4784.t1POLYCYSTIN FAMILY MEMBER0.99positive
g28439.t1COLLAGEN ALPHA0.99positive
g7.t1NEUROTRANSMITTER GATED ION CHANNEL0.99positive
g126.t1THROMBOSPONDIN0.99positive
g14389.t1TRANSMEMBRANE PROTEASE SERINE0.99positive
g2930.t1ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE0.99positive
g2113.t1--0.99positive
g27238.t1TRYPTASE-RELATED0.99positive
g34675.t1SI:CH211-266K2.10.99positive
g8733.t1CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN0.99positive
g3348.t1COLLAGEN ALPHA0.99positive
g2901.t1ANKYRIN REPEAT PROTEIN0.99positive
g31421.t1SI:CH211-266K2.10.99positive
g9349.t1SURFACE ANTIGEN BSPA-LIKE-RELATED0.99positive
g14024.t1LYSYL OXIDASE-LIKE-RELATED0.99positive
g6445.t1FIBRILLIN-RELATED0.99positive
g13536.t1SODIUM/CALCIUM EXCHANGER0.99positive
g12821.t1--0.99positive
g7744.t1SULFATE TRANSPORTER0.99positive
g35970.t1PENICILLIN-BINDING PROTEIN0.99positive
g6303.t1XANTHINE DEHYDROGENASE0.99positive
g13340.t1TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE0.99positive
g4678.t1CONTACTIN 50.99positive
g18807.t15-HYDROXYTRYPTAMINE RECEPTOR0.99positive
g853.t1--0.99positive
g34672.t1COLLAGEN ALPHA0.99positive
g4151.t1DYNEIN HEAVY CHAIN0.99positive
g10529.t1ORGANIC ANION TRANSPORTER0.98positive
g31974.t1ANK_REP_REGION DOMAIN-CONTAINING PROTEIN0.98positive
g7907.t1--0.98positive
g15181.t1--0.98positive
g18559.t1N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE0.98positive
g17867.t1CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN0.98positive
g21113.t1RIBONUCLEASE0.98positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 233 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
TOP