Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g667.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g667.t1
Gene ID Description PCC Relationship
g667.t1-1positive
g1064.t1MICROSOMAL PROSTAGLANDIN E SYNTHASE-20.96positive
g9735.t1ATAXIN-3-RELATED0.96positive
g9808.t1LYMPHOID-SPECIFIC HELICASE0.96positive
g14958.t1TOUCAN, ISOFORM A0.96positive
g16977.t1SEL-1-LIKE PROTEIN0.96positive
g9873.t1SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL0.96positive
g14416.t1COILED-COIL DOMAIN-CONTAINING PROTEIN 580.96positive
g14905.t1MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED0.96positive
g13256.t1RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY0.96positive
g5192.t1ATP-BINDING CASSETTE SUB-FAMILY C0.96positive
g16207.t1PROTEIN CBG266940.95positive
g14839.t1LIPASE0.95positive
g2501.t1N-ACETYLNEURAMINATE 9-O-ACETYLTRANSFERASE0.95positive
g36461.t1--0.95positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 63 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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