Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g6693.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g6693.t1
Gene ID Description PCC Relationship
g6693.t1UPF0598 PROTEIN C8ORF821positive
g6129.t1SJOEGREN SYNDROME NUCLEAR AUTOANTIGEN 10.97positive
g17935.t1NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-10.97positive
g1437.t139A RIBOSOMAL PROTEIN L50, MITOCHONDRIAL0.97positive
g15278.t1EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-10.97positive
g9735.t1ATAXIN-3-RELATED0.97positive
g34344.t1MITOCHONDRIAL CARRIER PROTEIN RIM20.97positive
g29028.t1TTC17 PROTEIN0.96positive
g6466.t1PHOSDUCIN-LIKE PROTEIN0.96positive
g366.t1KINETOCHORE-ASSOCIATED PROTEIN NSL1 HOMOLOG0.96positive
g9895.t1MITOCHONDRIAL RIBOSOMAL PROTEIN S250.96positive
g8443.t1IMPORTIN ALPHA0.96positive
g9882.t1ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 80.96positive
g22364.t1SIKE FAMILY MEMBER0.96positive
g1423.t1CARBOHYDRATE BINDING DOMAIN CONTAINING PROTEIN0.96positive
g352.t1--0.96positive
g36199.t1HISTONE DEACETYLASE HDAC1-RELATED0.95positive
g16173.t1HISTIDINE TRIAD HIT PROTEIN0.95positive
g15970.t1TROPONIN C-AKIN-1 PROTEIN0.95positive
g22005.t1ZINC FINGERS AND HOMEOBOXES PROTEIN 1, ISOFORM 20.95positive
g25745.t1CYSTINOSIN0.94positive
g20124.t1RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN0.93positive
g28749.t1AMINO ACID TRANSPORTER0.90positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 86 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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