Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g6840.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g6840.t1
Gene ID Description PCC Relationship
g6840.t1--1positive
g3382.t1--0.98positive
g3348.t1COLLAGEN ALPHA0.98positive
g13536.t1SODIUM/CALCIUM EXCHANGER0.98positive
g9452.t1E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED0.98positive
g12224.t1--0.98positive
g113.t1DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING0.98positive
g192.t1COLLAGEN ALPHA0.98positive
g14949.t1--0.98positive
g34663.t1SI:CH211-266K2.10.98positive
g27024.t1--0.98positive
g3350.t1CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN0.98positive
g19091.t1--0.98positive
g14023.t1LYSYL OXIDASE-LIKE-RELATED0.98positive
g7150.t1UNCHARACTERIZED0.98positive
g294.t1--0.98positive
g14881.t1--0.98positive
g29716.t1PROTEIN B, PUTATIVE-RELATED-RELATED0.95positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 50 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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