Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g6844.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g6844.t1
Gene ID Description PCC Relationship
g6844.t1PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED1positive
g4014.t1GUANYLYL CYCLASE0.99positive
g6232.t1POLYCYSTIN FAMILY MEMBER0.99positive
g27014.t1CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A0.99positive
g12614.t1BONUS, ISOFORM C-RELATED0.99positive
g16523.t1FI19480P10.99positive
g16747.t1--0.99positive
g12486.t1GLIAL CELLS MISSING RELATED/GLIDE0.99positive
g17696.t1--0.99positive
g3350.t1CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN0.99positive
g9452.t1E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED0.99positive
g27514.t1TRANSLATION ELONGATION FACTOR-RELATED0.99positive
g28286.t1--0.99positive
g27084.t1RADIAL SPOKE HEAD 1 HOMOLOG0.99positive
g28421.t1MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED0.99positive
g27130.t1BITESIZE, ISOFORM I0.99positive
g7481.t1--0.99positive
g192.t1COLLAGEN ALPHA0.99positive
g19151.t1VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM0.99positive
g15934.t1SI:CH211-266K2.10.99positive
g27475.t1--0.99positive
g20554.t1--0.99positive
g17435.t1VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A0.99positive
g17411.t1PROTEASE M14 CARBOXYPEPTIDASE0.99positive
g5720.t1VILLIN0.99positive
g14499.t15-HYDROXYTRYPTAMINE RECEPTOR0.99positive
g10560.t1BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST0.99positive
g16191.t1EPIDIDYMAL MEMBRANE PROTEIN E9-RELATED0.99positive
g28044.t1HOMEO BOX HB9 LIKE A-RELATED0.99positive
g28708.t1GABA-B RECEPTOR0.99positive
g7911.t1SYNAPSIN0.99positive
g2538.t1VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM0.99positive
g11127.t1MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED0.99positive
g16748.t1--0.98positive
g6189.t1LEUCOKININ RECEPTOR-RELATED0.98positive
g12982.t1--0.98positive
g27674.t1CARBONIC ANHYDRASE0.98positive
g14969.t1RAN BINDING PROTEIN 9-RELATED0.98positive
g31247.t1MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 30.98positive
g28360.t1FI19480P10.98positive
g28420.t1CYSTEINE-RICH SECRETORY PROTEIN-RELATED0.98positive
g15767.t1DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING0.98positive
g17102.t1SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B10.97positive
g2736.t1PIKACHURIN-LIKE PROTEIN0.96positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 243 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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