Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g6895.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g6895.t1
Gene ID Description PCC Relationship
g6895.t14.1 G PROTEIN1positive
g23523.t1--0.95positive
g13191.t1UNCHARACTERIZED0.95positive
g34939.t1TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS0.94positive
g24241.t1TETRASPANIN0.94positive
g2063.t1COLLAGEN ALPHA0.94positive
g16657.t1RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE0.94positive
g6524.t1CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN0.94positive
g34163.t1--0.93positive
g31444.t1--0.93positive
g17034.t1PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN0.92positive
g31472.t1PHD-TYPE DOMAIN-CONTAINING PROTEIN0.91positive
g6158.t1--0.86positive
g22745.t1--0.86positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 28 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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