Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g7.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g7.t1
Gene ID Description PCC Relationship
g7.t1NEUROTRANSMITTER GATED ION CHANNEL1positive
g2113.t1--1.00positive
g13536.t1SODIUM/CALCIUM EXCHANGER1.00positive
g7283.t1AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED0.99positive
g192.t1COLLAGEN ALPHA0.99positive
g15439.t1--0.99positive
g17806.t1COLLAGEN ALPHA0.99positive
g126.t1THROMBOSPONDIN0.99positive
g6445.t1FIBRILLIN-RELATED0.99positive
g4784.t1POLYCYSTIN FAMILY MEMBER0.99positive
g8733.t1CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN0.99positive
g10390.t1--0.99positive
g25713.t1--0.99positive
g10642.t1COLLAGEN ALPHA0.99positive
g35342.t1BRORIN FAMILY MEMBER0.99positive
g6614.t1COLLAGEN ALPHA0.99positive
g3925.t1UBIQUITIN-PROTEIN LIGASE E3C0.99positive
g27015.t1CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A0.99positive
g7546.t1--0.99positive
g3382.t1--0.99positive
g3648.t1RETICULON-LIKE PROTEIN0.99positive
g13454.t1NEUROTRANSMITTER GATED ION CHANNEL0.99positive
g14669.t1COLLAGEN ALPHA0.99positive
g27623.t1SERINE PROTEASE0.99positive
g2901.t1ANKYRIN REPEAT PROTEIN0.99positive
g26424.t1CYTOCHROME P450 FAMILY 30.99positive
g19151.t1VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM0.99positive
g12437.t1SOLUTE CARRIER FAMILY 20.99positive
g113.t1DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING0.99positive
g32703.t1ACTIN0.99positive
g17621.t1--0.99positive
g34672.t1COLLAGEN ALPHA0.99positive
g28150.t1--0.99positive
g5650.t1--0.99positive
g34663.t1SI:CH211-266K2.10.99positive
g15495.t1CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED0.99positive
g24840.t1--0.99positive
g3348.t1COLLAGEN ALPHA0.99positive
g15438.t1--0.99positive
g27124.t1TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 60.99positive
g16491.t1NADH-CYTOCHROME B5 REDUCTASE0.99positive
g9705.t1ENOLASE (DUF1399)0.99positive
g8155.t1L-FUCOSE KINASE0.99positive
g1102.t1VOLTAGE-GATED POTASSIUM CHANNEL0.99positive
g816.t1COLLAGEN0.98positive
g24689.t1FIBRINOGEN/TENASCIN/ANGIOPOEITIN0.98positive
g35072.t1BAND 7 PROTEIN-RELATED0.96positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 272 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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