Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g704.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g704.t1
Gene ID Description PCC Relationship
g704.t1METHYL-CPG BINDING PROTEIN, MBD1positive
g15643.t1TUBULIN0.99positive
g9780.t1--0.98positive
g7841.t1YEAST SPT2-RELATED0.98positive
g13385.t1SERINE/THREONINE-PROTEIN KINASE RIO10.98positive
g2094.t1--0.97positive
g10745.t1MACPF DOMAIN-CONTAINING PROTEIN0.97positive
g12395.t1LYSOSOMAL ACID LIPASE-RELATED0.97positive
g1944.t1--0.97positive
g6270.t1BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN FAMILY MEMBER0.97positive
g17432.t1COILED-COIL DOMAIN-CONTAINING PROTEIN 1500.96positive
g6450.t1DUAL SPECIFICITY PROTEIN PHOSPHATASE0.96positive
g3285.t1PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN0.96positive
g1971.t1COILED-COIL DOMAIN-CONTAINING PROTEIN 510.96positive
g8857.t1AGAP004327-PA0.96positive
g27052.t1THO2 PROTEIN0.96positive
g5566.t1LEUCINE-RICH REPEAT SERINE/THREONINE-PROTEIN KINASE 10.95positive
g19249.t1CXXC-TYPE ZINC FINGER PROTEIN 10.95positive
g7487.t126S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 30.95positive
g10627.t1RAD9, HUS1, RAD1-INTERACTING NUCLEAR ORPHAN PROTEIN 10.95positive
g14629.t1M-AAA PROTEASE-INTERACTING PROTEIN 1, MITOCHONDRIAL0.95positive
g23802.t1--0.95positive
g13755.t1--0.94positive
g28014.t1SERINE-THREONINE PROTEIN KINASE0.94positive
g2277.t13-DEHYDROQUINATE SYNTHASE0.94positive
g33532.t1WILMS' TUMOR 1-ASSOCIATING PROTEIN0.94positive
g8169.t1TROPONIN0.94positive
g17022.t1MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L490.94positive
g2558.t1--0.94positive
g13746.t1CALMODULIN-LYSINE N-METHYLTRANSFERASE0.93positive
g13401.t1P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN0.93positive
g18189.t1SULFATASE MODIFYING FACTOR 1, 20.93positive
g29441.t1--0.93positive
g27143.t1PROGRAMMED CELL DEATH PROTEIN 70.93positive
g34177.t1--0.92positive
g28095.t1ZINC FINGER HIT DOMAIN CONTAINING PROTEIN 2 PROTEIN FON -RELATED0.92positive
g14311.t1TGF-BETA INDUCED APOPTOSIS PROTEIN0.91positive
g13268.t1N-ALPHA-ACETYLTRANSFERASE0.90positive
g2142.t1SYNTAXIN0.89positive
g7939.t1MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED0.88positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 276 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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