Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g7071.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g7071.t1
Gene ID Description PCC Relationship
g7071.t1FAM11A, B PROTEIN1positive
g14848.t1UBIQUITIN THIOLESTERASE PROTEIN OTUB0.97positive
g27535.t1--0.95positive
g26664.t1SPERMATOGENESIS ASSOCIATED 11-RELATED0.95positive
g20491.t1CARBON CATABOLITE REPRESSOR PROTEIN 40.95positive
g8033.t1CENTROMERE PROTEIN L0.95positive
g6363.t1NUCLEAR TRANSPORT FACTOR 20.95positive
g7567.t1GEO07735P1-RELATED-RELATED0.94positive
g17646.t1--0.94positive
g29179.t1CARBON CATABOLITE REPRESSOR PROTEIN 40.94positive
g31092.t1--0.94positive
g27322.t1UNCHARACTERIZED0.93positive
g13350.t1TRANSMEMBRANE PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA0.93positive
g16368.t1UBIQUITIN-CONJUGATING ENZYME E20.93positive
g22005.t1ZINC FINGERS AND HOMEOBOXES PROTEIN 1, ISOFORM 20.93positive
g33745.t1ANKYRIN REPEAT PROTEIN0.92positive
g17137.t1--0.92positive
g7607.t1UNCHARACTERIZED0.92positive
g9051.t1ACYL-MALONYL CONDENSING ENZYME-RELATED0.91positive
g27852.t1INOSITOL-TETRAKISPHOSPHATE 1-KINASE0.91positive
g27513.t1GLUCONOKINASE-RELATED0.90positive
g29092.t1CARBON CATABOLITE REPRESSOR PROTEIN 40.90positive
g36279.t1CELL FATE DETERMINING PROTEIN MAB21-RELATED0.89positive
g3039.t1GAMMA-SECRETASE SUBUNIT APH-10.88positive
g27909.t1TRACE AMINE-ASSOCIATED RECEPTOR 19N-RELATED0.83positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 89 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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