Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g7257.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g7257.t1
Gene ID Description PCC Relationship
g7257.t1RING FINGER PROTEIN 1271positive
g11552.t1METHYL-CPG BINDING PROTEIN, DROSOPHILA0.96positive
g11629.t1KNIRPS-RELATED PROTEIN-RELATED0.96positive
g29834.t1HAMARTIN0.96positive
g21368.t1FACIOGENITAL DYSPLASIA PROTEIN0.95positive
g9548.t1TUBBY-RELATED0.95positive
g10462.t1NIPPED-B-LIKE PROTEIN DELANGIN SCC2-RELATED0.95positive
g12759.t1SLINGSHOT PROTEIN PHOSPHATASE HOMOLOG0.95positive
g11437.t1AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 20.95positive
g20916.t1GTP-BINDING PROTEIN ALPHA SUBUNIT0.95positive
g16960.t1--0.95positive
g6288.t1GUANYL-NUCLEOTIDE EXCHANGE FACTOR0.95positive
g11711.t1BATTENIN0.95positive
g34775.t1JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN0.94positive
g11677.t1DOUBLECORTIN DOMAIN-CONTAINING PROTEIN 10.94positive
g12364.t1FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 1000.94positive
g27712.t1SH3-BINDING0.94positive
g335.t1VACUOLAR PROTEIN SORTING 540.94positive
g18946.t1--0.94positive
g4202.t1ANAPHASE-PROMOTING COMPLEX SUBUNIT 20.94positive
g16961.t1ABC TRANSPORTER G FAMILY MEMBER 280.94positive
g3264.t1ACTIN-BINDING LIM PROTEIN0.94positive
g22614.t1--0.94positive
g34387.t1--0.94positive
g334.t1VACUOLAR PROTEIN SORTING 540.93positive
g35074.t1DOCKING PROTEIN RELATED0.93positive
g1857.t1ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL0.89positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 116 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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