Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g7280.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g7280.t1
Gene ID Description PCC Relationship
g7280.t1AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED1positive
g5747.t1ATAXIA TELANGIECTASIA MUTATED ATM -RELATED0.99positive
g3872.t1PROLINE-RICH TRANSMEMBRANE PROTEIN 4-RELATED0.99positive
g19186.t1TNF RECEPTOR ASSOCIATED FACTOR0.99positive
g4434.t1FIBRINOGEN/TENASCIN/ANGIOPOEITIN0.99positive
g27014.t1CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A0.99positive
g27514.t1TRANSLATION ELONGATION FACTOR-RELATED0.99positive
g17191.t1G-PROTEIN COUPLED RECEPTOR0.99positive
g22433.t1SLR5058 PROTEIN0.99positive
g4055.t1--0.99positive
g22956.t1--0.99positive
g17435.t1VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A0.99positive
g16747.t1--0.99positive
g9429.t1RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 10.99positive
g4327.t1TYROSINE-PROTEIN KINASE RECEPTOR0.99positive
g8850.t1--0.99positive
g2538.t1VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM0.98positive
g5542.t1XANTHINE DEHYDROGENASE0.98positive
g2384.t1SET AND MYND DOMAIN-CONTAINING PROTEIN 40.98positive
g24545.t1GLYCOSYLTRANSFERASE WBBK-RELATED0.98positive
g2432.t1NEUROTRANSMITTER GATED ION CHANNEL0.98positive
g1533.t1NUCLEAR HORMONE RECEPTOR0.98positive
g28006.t1OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR0.98positive
g13519.t1GRANULIN0.98positive
g3424.t1LEUCINE RICH REPEAT FAMILY PROTEIN0.98positive
g11349.t1ALDO/KETO REDUCTASE0.98positive
g33594.t1RETROTRANSPOSON0.98positive
g27354.t1GLYCOSYL HYDROLASE0.98positive
g14132.t1TRANSCRIPTIONAL REPRESSOR PROTEIN YY0.98positive
g8851.t1--0.98positive
g28839.t1--0.95positive
g17057.t1EPHRIN TYPE-B RECEPTOR0.94positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 122 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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