Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g74.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g74.t1
Gene ID Description PCC Relationship
g74.t1COILED-COIL DOMAIN-CONTAINING PROTEIN 1581positive
g15034.t126S PROTEASOME REGULATORY SUBUNIT0.98positive
g1080.t1RAS GTPASE-ACTIVATING PROTEINS0.97positive
g11264.t1PRE-MRNA SPLICING FACTOR0.97positive
g8463.t1NUCLEOLAR COMPLEX PROTEIN 30.97positive
g2621.t1--0.97positive
g17649.t1NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 8, MITOCHONDRIAL0.97positive
g396.t1GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEINS-INTERACTING PROTEIN 1 GADD45GIP10.96positive
g12697.t1COATOMER SUBUNIT EPSILON0.96positive
g143.t1--0.95positive
g32162.t1METHANETHIOL OXIDASE0.95positive
g21456.t126S PROTEASOME REGULATORY SUBUNIT0.95positive
g33940.t1--0.95positive
g26946.t1PROTEASOME SUBUNIT ALPHA/BETA0.95positive
g14327.t1MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S100.95positive
g19466.t1UNCHARACTERIZED0.95positive
g13779.t1MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM400.95positive
g717.t160S RIBOSOMAL PROTEIN L240.95positive
g5997.t1--0.95positive
g33910.t1UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX UBIQUINONE-BINDING PROTEIN QP-C0.94positive
g22682.t1BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN BRCA20.94positive
g15799.t1REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT0.94positive
g30074.t1--0.94positive
g3475.t1DNA REPAIR/RNA PROCESSING CPSF FAMILY0.94positive
g27963.t126S PROTEASOME REGULATORY SUBUNIT0.93positive
g25529.t1--0.93positive
g26848.t1ATP SYNTHASE COUPLING FACTOR 6, MITOCHONDRIAL0.93positive
g16326.t1CENTROSOMAL PROTEIN 20.93positive
g24006.t1COLLAGEN ALPHA0.92positive
g34948.t1ATP-BINDING CASSETTE SUB-FAMILY B0.89positive
g423.t1TROPOMYOSIN0.89positive
g30527.t1--0.88positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 173 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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