Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g7546.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g7546.t1
Gene ID Description PCC Relationship
g7546.t1--1positive
g15439.t1--1.00positive
g10642.t1COLLAGEN ALPHA1.00positive
g10644.t1COLLAGEN1.00positive
g3648.t1RETICULON-LIKE PROTEIN0.99positive
g10672.t1--0.99positive
g16163.t1TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 130.99positive
g31660.t1SH3 DOMAIN-CONTAINING0.99positive
g4434.t1FIBRINOGEN/TENASCIN/ANGIOPOEITIN0.99positive
g34854.t1SULFOTRANSFERASE DOMAIN-CONTAINING PROTEIN0.99positive
g17731.t1TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS0.99positive
g27864.t1TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS0.99positive
g6783.t1OPSIN0.99positive
g32102.t1EXPANSIN-LIKE PROTEIN 20.99positive
g9043.t1METAXIN RELATED0.99positive
g4710.t1THYROTROPIN-RELEASING HORMONE RECEPTOR0.99positive
g11133.t1CUB DOMAIN-CONTAINING PROTEIN0.99positive
g31603.t1--0.99positive
g3877.t1IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX0.99positive
g27828.t1--0.99positive
g18961.t1G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER0.99positive
g418.t1VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM0.99positive
g27084.t1RADIAL SPOKE HEAD 1 HOMOLOG0.99positive
g2594.t1SYNAPTOTAGMIN0.99positive
g32030.t1TRANSMEMBRANE PROTEIN 1630.99positive
g27676.t1NEUROTRANSMITTER GATED ION CHANNEL0.99positive
g7906.t1POLYCYSTIN FAMILY MEMBER0.99positive
g6890.t1UNCHARACTERIZED0.99positive
g3925.t1UBIQUITIN-PROTEIN LIGASE E3C0.99positive
g23600.t1G PROTEIN-COUPLED RECEPTOR0.99positive
g4265.t1SYNAPTOTAGMIN0.99positive
g14919.t1ACROSIN-RELATED0.99positive
g32376.t1LIPOXYGENASE0.99positive
g7.t1NEUROTRANSMITTER GATED ION CHANNEL0.99positive
g27015.t1CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A0.99positive
g2113.t1--0.99positive
g2117.t1--0.99positive
g16362.t1KELCH PROTEIN0.99positive
g5747.t1ATAXIA TELANGIECTASIA MUTATED ATM -RELATED0.99positive
g27468.t1SOLUTE CARRIER FAMILY 22 MEMBER0.99positive
g12437.t1SOLUTE CARRIER FAMILY 20.99positive
g1810.t1LEUCOKININ RECEPTOR-RELATED0.99positive
g13144.t1OVOCHYMASE-RELATED0.99positive
g4055.t1--0.99positive
g1988.t1HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR0.99positive
g28319.t1CYSTEINE-RICH SECRETORY PROTEIN-RELATED0.99positive
g16328.t1ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR0.99positive
g4688.t1OVOCHYMASE-RELATED0.99positive
g12092.t1RIBULOKINASE0.99positive
g1549.t1METHYLTRANSFERASE0.99positive
g1952.t1--0.99positive
g5253.t1IONOTROPIC GLUTAMATE RECEPTOR0.99positive
g25392.t1MONOCARBOXYLATE TRANSPORTER0.96positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 395 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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