Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g7913.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g7913.t1
Gene ID Description PCC Relationship
g7913.t1SYNAPSIN1positive
g6876.t1CYCLIC NUCLEOTIDE PHOSPHODIESTERASE0.99positive
g27014.t1CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A0.99positive
g16324.t1ATP-BINDING CASSETTE SUB-FAMILY C0.99positive
g7884.t1--0.99positive
g19151.t1VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM0.99positive
g12614.t1BONUS, ISOFORM C-RELATED0.99positive
g12603.t1--0.99positive
g6416.t1--0.99positive
g7797.t1GLUTAMATE SEMIALDEHYDE DEHYDROGENASE0.99positive
g9043.t1METAXIN RELATED0.99positive
g1102.t1VOLTAGE-GATED POTASSIUM CHANNEL0.99positive
g28694.t1OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR0.99positive
g4014.t1GUANYLYL CYCLASE0.99positive
g15495.t1CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED0.98positive
g17435.t1VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A0.98positive
g1938.t1LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED0.98positive
g5542.t1XANTHINE DEHYDROGENASE0.98positive
g22649.t1RETROTRANSPOSON0.98positive
g31641.t152 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED0.98positive
g16088.t1PROTEIN CBG053490.98positive
g8826.t1--0.98positive
g2432.t1NEUROTRANSMITTER GATED ION CHANNEL0.98positive
g14969.t1RAN BINDING PROTEIN 9-RELATED0.98positive
g11981.t1NEUROTRANSMITTER GATED ION CHANNEL0.98positive
g6875.t1CYCLIC NUCLEOTIDE PHOSPHODIESTERASE0.98positive
g18478.t1CALPAIN0.98positive
g7790.t1SOLUTE CARRIER FAMILY 170.98positive
g2735.t1PIKACHURIN-LIKE PROTEIN0.97positive
g14970.t1--0.95positive
g22673.t1--0.93positive
g35846.t1REVERSE TRANSCRIPTASES0.93positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 129 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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