Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g8024.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g8024.t1
Gene ID Description PCC Relationship
g8024.t1PEPTIDASE S491positive
g8755.t1--0.94positive
g3902.t1LEUCINE AMINOPEPTIDASE-RELATED0.92positive
g21457.t1SEC100.91positive
g34967.t1GTP-BINDING PROTEIN-RELATED0.91positive
g3269.t1DEHYDROGENASE RELATED0.90positive
g20596.t1ACYL CARRIER PROTEIN0.90positive
g15083.t1NUCLEOSIDE DIPHOSPHATE KINASE0.89positive
g341.t1NOTCH LIGAND FAMILY MEMBER0.89positive
g7132.t1TIP1200.89positive
g10447.t1FRINGE-RELATED0.89positive
g35048.t1ENOYL-COA HYDRATASE-RELATED0.89positive
g7234.t1UNCHARACTERIZED0.89positive
g27495.t1MYOSIN LIGHT CHAIN 1, 30.88positive
g8533.t1PROLINE-RICH TRANSMEMBRANE PROTEIN 4-RELATED0.88positive
g6915.t1UNCHARACTERIZED0.88positive
g3243.t1NAD(P) TRANSHYDROGENASE0.88positive
g4672.t1PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 470.87positive
g34668.t1PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER0.86positive
g35818.t1BADF TYPE ATPASE DOMAIN-CONTAINING PROTEIN0.86positive
g9639.t1--0.86positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 91 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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