Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g8440.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g8440.t1
Gene ID Description PCC Relationship
g8440.t1ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 181positive
g20671.t1PRE-MRNA SPLICING FACTOR PRP80.93positive
g3945.t1FMS INTERACTING PROTEIN0.93positive
g6578.t1CLEAVAGE STIMULATION FACTOR SUBUNIT 20.92positive
g2307.t1CYCLIN0.90positive
g10892.t1--0.89positive
g33532.t1WILMS' TUMOR 1-ASSOCIATING PROTEIN0.86positive
g7613.t1CYTOSOLIC RESINIFERATOXIN BINDING PROTEIN RBP-260.86positive
g2558.t1--0.86positive
g388.t1ZINC FINGER PROTEIN-LIKE 10.85positive
g26492.t1HISTONE DEACETYLASE 2-RELATED0.85positive
g31982.t1PESCADILLO - RELATED0.84positive
g1022.t1ATP-DEPENDENT RNA HELICASE RHLE-RELATED0.83positive
g785.t1SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 20.82positive
g3167.t1LD11652P0.81positive
g16551.t1PRE-MRNA-SPLICING FACTOR RBM220.80positive
g33703.t1CENTROSOMAL PROTEIN OF 44 KDA0.80positive
g13798.t1CHARGED MULTIVESICULAR BODY PROTEIN0.75positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 65 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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