Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g8461.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g8461.t1
Gene ID Description PCC Relationship
g8461.t1--1positive
g3592.t1SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA0.94positive
g7540.t1--0.94positive
g16730.t1PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC10.94positive
g29170.t1GTP-BINDING PROTEIN-RELATED0.94positive
g17188.t1UBIQUITINATION FACTOR E40.94positive
g12735.t1GOLGI MEMBRANE PROTEIN YIP10.94positive
g34813.t1RPE-SPONDIN0.94positive
g12970.t1TRANSMEMBRANE 9 SUPERFAMILY PROTEIN0.94positive
g10026.t1PEROXISOMAL BIOGENESIS FACTOR 110.94positive
g14797.t1ATP-BINDING TRANSPORT PROTEIN-RELATED0.94positive
g3373.t1ATP-DEPENDENT RNA HELICASE RHLE-RELATED0.93positive
g30855.t126S PROTEASOME REGULATORY SUBUNIT0.93positive
g9776.t1COLLAGEN ALPHA0.93positive
g17149.t1BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE0.93positive
g4209.t1FCH AND DOUBLE SH3 DOMAINS PROTEIN0.92positive
g574.t1CHONDROITIN SYNTHASE0.92positive
g8822.t1PIKACHURIN-LIKE PROTEIN0.92positive
g9772.t1COLLAGEN ALPHA0.92positive
g29605.t1SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER0.90positive
g28992.t1BIFUNCTIONAL TH2 PROTEIN0.73positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 67 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
TOP