Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g8495.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g8495.t1
Gene ID Description PCC Relationship
g8495.t1SERINE/THREONINE-PROTEIN KINASE1positive
g27061.t1RAB GDP-DISSOCIATION INHIBITOR0.98positive
g2719.t1GLR0591 PROTEIN0.98positive
g9271.t1SERINE/THREONINE-PROTEIN KINASE NEK0.97positive
g12346.t1GABA-B RECEPTOR0.97positive
g30127.t1--0.97positive
g17292.t1ENDOGLIN/TGF-BETA RECEPTOR TYPE III0.97positive
g4748.t1--0.97positive
g32099.t1METABOTROPIC GLUTAMATE RECEPTOR0.97positive
g11768.t1AAA-FAMILY ATPASE0.97positive
g6644.t1REGULATOR OF G PROTEIN SIGNALING0.97positive
g12220.t1HYDROLASE OF PHP SUPERFAMILY-RELATED PROTEIN0.97positive
g1819.t1CALPAIN0.97positive
g21652.t1P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE0.97positive
g1197.t1DOUBLE-STRAND BREAK REPAIR RAD50 ATPASE, PUTATIVE-RELATED0.96positive
g19119.t1RIKEN CDNA 1700001C19 GENE0.96positive
g23413.t1FORMIN-BINDING PROTEIN 40.96positive
g23590.t1TYROSINE-PROTEIN KINASE RECEPTOR0.96positive
g6872.t1ALPHA-MANNOSIDE BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE0.96positive
g16583.t1--0.96positive
g16508.t1VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 370.96positive
g7311.t1CENTROMERE PROTEIN E0.96positive
g13795.t1PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 270.96positive
g27458.t1NEUROPEPTIDE Y RECEPTOR0.96positive
g5349.t1FAMILY WITH SEQUENCE SIMILARITY 216 MEMBER A0.96positive
g30862.t1BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE0.96positive
g22212.t1PHD-TYPE DOMAIN-CONTAINING PROTEIN0.95positive
g28149.t1--0.95positive
g34939.t1TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS0.95positive
g10773.t1--0.92positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 109 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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