Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g8516.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g8516.t1
Gene ID Description PCC Relationship
g8516.t1LD33804P1positive
g26473.t1EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H0.96positive
g14276.t1YL-1 PROTEIN TRANSCRIPTION FACTOR-LIKE 10.95positive
g5212.t1POLYCOMB GROUP PROTEIN PC0.95positive
g8665.t1HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED0.95positive
g12416.t1LIM DOMAIN-CONTAINING PROTEIN0.95positive
g21226.t1TROPOMYOSIN0.94positive
g23119.t1TRANSLATION INITIATION FACTOR-RELATED0.94positive
g20241.t1HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER0.94positive
g28599.t128 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN PDGF-ASSOCIATED PROTEIN0.93positive
g10086.t1TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN0.93positive
g3036.t1--0.93positive
g8867.t1RIBOSOMAL PROTEIN L7AE FAMILY MEMBER0.93positive
g8716.t160 KDA RIBONUCLEOPROTEIN SSA/RO0.93positive
g18374.t1PRE-MRNA-PROCESSING FACTOR 190.92positive
g35155.t1CLEAVAGE AND POLYADENYLATION SPECIFIC FACTOR0.92positive
g28199.t1E3 UBIQUITIN-PROTEIN LIGASE TRIP120.92positive
g30678.t1CHROMOSOME 20 ORF85 FAMILY MEMBER0.91positive
g12007.t1GENERAL TRANSCRIPTION FACTOR IIIC, POLYPEPTIDE 50.90positive
g9626.t1ER LUMEN PROTEIN RETAINING RECEPTOR0.89positive
g7231.t1VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 10.89positive
g28550.t1EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G0.89positive
g23834.t1LIGAND BINDING DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14370)-RELATED0.89positive
g18043.t1ZGC:1951700.87positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 96 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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